 San Francisco 49ers
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|---|---|---|---|---|
| Return Date | Player | Status | Prognosis | Comment |
| 3/1/2025 | Chris Conley | QUESTIONABLE | Elbow | |
| 2/16/2025 | Tajae Sharpe | QUESTIONABLE | Undisclosed | |
| 5/1/2025 | Christian McCaffrey | QUESTIONABLE | Knee - PCL | |
| 2/16/2025 | Chris Thompson | QUESTIONABLE | Undisclosed | |
| 3/1/2025 | Deebo Samuel | QUESTIONABLE | Ribs | |
| 8/1/2025 | Brandon Aiyuk | QUESTIONABLE | Knee - ACL + MCL | |
| 2/16/2025 | Jaylon Moore | QUESTIONABLE | Undisclosed | |
| 5/1/2025 | Elijah Mitchell | QUESTIONABLE | Hamstring | |
| 2/16/2025 | Frank Darby | QUESTIONABLE | Undisclosed | |
| 5/1/2025 | Brock Purdy | QUESTIONABLE | Elbow | |
| 3/1/2025 | Jordan Mason | QUESTIONABLE | Ankle | |
| 5/1/2025 | Isaac Guerendo | QUESTIONABLE | Knee - MCL | |
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