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 San Francisco 49ers
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| Return Date | Player | Status | Prognosis | Comment |
| 8/27/2026 | Kyle Juszczyk | QUESTIONABLE | Finger | |
| 9/10/2026 | Mike Evans | QUESTIONABLE | Groin | |
| 8/27/2026 | Christian McCaffrey | QUESTIONABLE | Undisclosed | |
| 9/10/2026 | George Kittle | QUESTIONABLE | Achilles | |
| 8/27/2026 | Christian Kirk | QUESTIONABLE | Calf | |
| 7/1/2026 | Andy Isabella | QUESTIONABLE | Ankle | |
| 8/27/2026 | Brandon Aiyuk | RESERVE-DNR | Knee - ACL + MCL | |
| 2/15/2027 | Patrick Taylor Jr. | IR | Undisclosed | |
| 8/27/2026 | Jacob Cowing | QUESTIONABLE | Groin | |
| 2/15/2027 | Ricky Pearsall | IR | Knee - PCL | |
| 9/13/2026 | Tanner McLachlan | QUESTIONABLE | Undisclosed | |
| 8/27/2026 | Isaac Guerendo | PUP-P | Pectoral | |
| 8/27/2026 | Jordan James | QUESTIONABLE | Ribs | |
| 9/10/2026 | Kurtis Rourke | QUESTIONABLE | Ribs | |
| 8/27/2026 | De'Zhaun Stribling | QUESTIONABLE | Shoulder | |
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